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KMID : 0043320230460110825
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Archives of Pharmacal Research
2023 Volume.46 No. 11 p.825 ~ p.854
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Phytochemistry and pharmacology of plants in the genus Chaenomeles
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Ruoling Xu
Mengting Kuang
Ning Li
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Abstract
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Chaenomeles plants belong to the Rosaceae family and include fi ve species, Chaenomeles speciosa (Sweet) Nakai, Chaenomelessinensis (Thouin) Koehne, Chaenomeles japonica (Thunb.) Lindl, Chaenomeles cathayensis (Hemsl.) Schneid andChaenomeles thibetica Yu. Chaenomeles plants are found and cultivated in nearly every country worldwide. China servesas both the origin and distribution hub for the plants in the Chaenomeles genus, and all Chaenomeles species except for C.
japonica are indigenous to China. Chaenomeles spp. is a type of edible medicinal plant that has been traditionally used inChina to treat various ailments, such as rheumatism, cholera, dysentery, enteritis, beriberi, and scurvy. A variety of chemicalconstituents have been extracted from this genus, including terpenoids, phenolics, fl avonoids, phenylpropanoids and theirderivatives, benzoic acid derivatives, biphenyls, oxylipins, and alkaloids. The biological activity of some of these constituentshas already been evaluated. Pharmacological investigations have demonstrated that the plants in the genus Chaenomelesexhibit anti-infl ammatory, analgesic, antioxidant, antihyperglycemic, antihyperlipidemic, gastrointestinal protective, antitumor,immunomodulatory, antibacterial, antiviral, hepatoprotective, neuroprotective and other pharmacological activities.
The objective of this review is to provide a comprehensive and up-to-date summary of the available information on the genusChaenomeles to serve as a valuable reference for further investigations.
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KEYWORD
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Chaenomeles genus, Phytochemistry, Pharmacological activities
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